How does the cell on the tip of my nose know to perform all the functions of a cell on the tip of my nose? How does it know that it isn’t a cell on the side of my nose (or my liver, brain, etc.) : askscience

This is fascinating!

Finally my degree (Molecular Genetics) can be useful!It’s all about protein gradients. It’s part of why life is mostly symmetrical or radial. You have a point of origin, let’s say a shoulder area, producing a particular protein during development. As the cells near it replicate to form an arm, the protein made at the origin spreads into them. The further the cells are from the origin, the less protein they have. Eventually, the cells are far enough away that the lack of that protein signals that the new cells being formed should be hand cells. Those hand cells then function as a new point of origin for a different protein radiating outward, which when present on its own forms finger cells and when mixed with the original shoulder protein forms wrist cells. At about a 50/50 mix of hand/shoulder proteins, elbow cells form.This is a very simplified explanation, as the truth involves the interaction of countless protein gradients and combinations from tons of origin points, but it’s the general way that your body forms and differentiates.So the cells on the tip of your nose are far enough from the point where your nose meets your face and have little enough of one or, more likely, five thousand nose proteins that they know they should be tip of nose cells as opposed to anything else. They’re obviously not getting “please become feet” proteins because the origin cells for those are much too far away.Hope that helps.

Source:

More great discussion here:
How does the cell on the tip of my nose know to perform all the functions of a cell on the tip of my nose? How does it know that it isn’t a cell on the side of my nose (or my liver, brain, etc.) : askscience

Five programming problems every Software Engineer should be able to solve in less than 1 hour

Five programming problems every Software Engineer should be able to solve in less than 1 hour Whenever I post a job request for a Software Engineer position, applications start trickling in really quick. What bothers me is that several applicants will invariably have no idea of what “programming” means.

Source: Five programming problems every Software Engineer should be able to solve in less than 1 hour

blog.reddit — what’s new on reddit: We’re sharing our company’s core values with the world

Reddit has some solid core values.

Source: blog.reddit — what’s new on reddit: We’re sharing our company’s core values with the world

 

  1. 1. Remember the human

    • Be authentic, passionate, and empathetic.
    • Treat others as you would in person, and remember we all make mistakes.
    • Champion diversity.
    • Default to transparency, and when you can’t be transparent, be honest.
  2. 2. Give people voices

    • Create a safe space to encourage participation.
    • Embrace diversity of viewpoints.
    • Allow freedom of expression.
    • Be stewards, not dictators. The community owns itself.
  3. 3. Respect anonymity and privacy

    • You are not required to share more than you are comfortable with.
    • Having information doesn’t give you a license to use it.
    • Allow people to be as anonymous as they choose, including ourselves.
    • Value the candor afforded by anonymity.
  4. 4. Embrace experimentation

    • Don’t let “that’s the way it’s always been done” be a reason.
    • Seek new ways to be better.
    • Be willing to try new things and fail.
    • But remember wheels don’t always need reinventing.
  5. 5. Make deliberate decisions

    • Make all decisions within the framework of larger goals.
    • It’s better to make an unpopular, deliberate decision than to make a consensus decision on a whim.
    • Consciously explore options and impacts of potential paths.
    • Voice disagreement; acknowledge that dissension is okay.
  6. 6. Be doers

    • Turn ideas into actions and get things done.
    • Don’t be paralyzed by the status quo.
    • Find the balance between perfection and progress.
    • Build for the future and leave things better than you found them.
  7. 7. The spirit of Lambeosaurus embiggens us all

    • Work is better when you’re having fun.
    • Don’t take ourselves too seriously.
    • Celebrate the good: recognize successes and reward accomplishments.
    • There must be four subpoints to each value.

We are proud to share our values with the world, and they are now also displayed on our about pageand linked to in our footer

HTTrack Website Copier – Download Entire Site(s) – Open Source – Free

Downloads entire sites via command line / shell / terminal that thing you type commands into.

It allows you to download a World Wide Web site from the Internet to a local directory, building recursively all directories, getting HTML, images, and other files from the server to your computer. HTTrack arranges the original site’s relative link-structure. Simply open a page of the "mirrored" website in your browser, and you can browse the site from link to link, as if you were viewing it online. HTTrack can also update an existing mirrored site, and resume interrupted downloads. HTTrack is fully configurable, and has an integrated help system.

via HTTrack Website Copier – Free Software Offline Browser (GNU GPL).

A blind man and a double amputee planted 10,000 trees. What’s your excuse?

We need more of these peoples… :)

“I am his hands. He is my eyes.”
Jia Haixa talks of his symbiotic relationship with his friend Jia Wenqi — a double amputee. The pair work together to plant trees in Yeli village, just outside of Shijiazhuang city, northern China.

Losing his sight in one eye to congenital cataracts, and later his right eye in a work-related accident, Jia Haixa is completely blind. The friends approached the local government and leased a 7.5 acre stretch of land along the riverbank. They hope to transform it by planting 1,000 trees every year, and have been doing that for a decade.
Planting the trees helps them to earn money, having both struggled to find work individually due to their handicaps. They also hope to benefit future generations with their environmental efforts.
Fortunately, the local authorities allow them to live rent-free, which is a great gesture given their poor living conditions.
http://mashable.com/2015/03/31/blind-man-armless-friend-environmentalists/[1]

A blind man and a double amputee planted 10,000 trees. What's your excuse?.

some tips for living better.

Here are 6 signs you may be living an imbalanced life

Finding it hard to concentrate on the positive
Eating foods you know don’t make you feel good
Not wanting to get out of bed or not wanting to go to sleep
Not doing the things you love and things that feel good
Using you phone, computer or other vices as distractions to avoid what ‘is’
Feeling unsettled, anxious or nervous
Having a bank of self-care techniques will help you in these moments of imbalance. It often only takes a slight change in perspective and feeling to get back on track.

Here are 11 amazing ways to help you feel like the superhuman you are.

1. Make a list of the things that make you happy – Do them

2. Make a list of the foods that make you feel great – Eat them

3. Light some candles and listen to your favourite music

4. Tap it out using EFT (Emotional Freedom Technique)

5. Go to a yoga class

6. Sweat – use the sauna or get some exercise

7. Get a massage or give yourself a head-to-toe oil or lotion massage

8. Get out nature

9. Focus on small tasks that you can complete rather than feeling overwhelmed with the larger picture

10. Spend some time with babies or kids

http://www.youngandraw.com/11-incredible-ways-feel-superhuman-every-day/

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